Interferon Panel (9-Plex)
Indications: Use this test to assess the interferon response in viral infections, autoinflammatory interferopathies, and autoimmune diseases
ANALYTES / BIOMARKERS
IFNα2, IFNβ, IFNγ, IFNγR1, IFNε, IFNλ1, IFNλ2, IFNλ3, IFNω
TURNAROUND-TIME (TAT)
1-5 Days
SAMPLE STABILITY
Samples collected for immune-related biomarkers are stable for approximately 1 year if kept frozen (-80˚C preferred). Samples that are left at room temperature beyond 30 minutes during sample collection or are stored at 4˚C are not stable and are not acceptable unless they are processed in BD P-100 tubes.
PROCEDURE / TECHNIQUE
Luminex® 100/200 (Addressable LASER Bead Immunoassay)
REFERENCE RANGE
Available for plasma-EDTA and serum samples.
CLINICAL ASSOCIATIONS
Use this test to identify relevant therapy targets, determine disease mechanisms, and diagnose or monitor the following conditions:
- Viral Infections: Useful for detecting acute and chronic viral infections such as hepatitis B, hepatitis C, HIV, and respiratory viral infections including influenza and COVID-19.
- Autoimmune Diseases: Helps in diagnosing and managing autoimmune conditions like systemic lupus erythematosus (SLE), multiple sclerosis (MS), rheumatoid arthritis, and type 1 diabetes.
- Chronic Inflammatory Diseases: Assists in identifying chronic inflammatory conditions such as Crohn’s disease, psoriasis, and chronic obstructive pulmonary disease (COPD).
- Cancer Immunotherapy Monitoring: Monitors therapeutic response in cancer treatments, particularly for melanoma and renal cell carcinoma.
- Severe or Chronic Inflammation: Useful in conditions such as prolonged or periodic fever, severe or chronic inflammation, organ dysfunction, and investigation of cytokine storms seen in hemophagocytic lymphohistiocytosis (HLH) and related conditions.
The interpretation of these test results should be correlated with clinical findings and other diagnostic tests. Cytokine levels can vary due to many biological, physiological, and diurnal factors; their clinical significance must be assessed by a qualified healthcare professional. This information is not intended to be used as the sole basis for diagnosis or treatment decisions.
See example report below.